For centuries, people of almost every culture have used chemical agents to induce sleep, relieve stress, and calm anxiety. While alcohol is one of the oldest and most universal agents used for these purposes, hundreds of substances have been developed that produce central nervous system depression.

These drugs have been referred to as downers, sedatives, hypnotics, minor tranquilizers, anxiolytics, and anti-anxiety medications. Unlike many classes of drugs, depressants are rarely produced in illegal warehouses, but in pharmaceutical laboratories. While these drugs are made for legitimate medical needs of patients, they are often abused with dangerous results.

Types of Depressants

• Barbiturates
• Benzodiazepines
• Quaaludes

Last reviewed March 2009.
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